Simethicone

Comprehensive clinical interaction and dietary monograph for Simethicone (Simethicone).

Generic Active Chemical: Simethicone

Brand Formulations:Alka-Seltzer Anti-GasColic DropsColiconDegasFlatulex DropsGas AideGas-XGenasymeMaalox Anti-GasMajorconMicon-80Mylanta GasMylavalMyliconMytab GasPhazymeSonoRxAlamag Plus (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Aldroxicon (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Almacone (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Balanta (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Balox Plus (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Dixlanta (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Flatulex Tablets (containing Activated Charcoal, Simethicone)Gas-X with Maalox (containing Calcium Carbonate, Simethicone)Gelusil (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Gen-Lanta (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Imodium Advanced (containing Loperamide, Simethicone)Losospan Plus (containing Magaldrate, Simethicone)Low Sodium Plus (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Lowsium Plus (containing Magaldrate, Simethicone)Maalox Plus (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Magaant (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Magagel Plus (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Magaldrate Plus (containing Magaldrate, Simethicone)Magalox Plus (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Maldroxal Plus (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Masanti (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Mintox Plus (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Mygel (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Mylagel (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Mylagen (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Mylanta (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Ri-Gel II (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Ri-Mox Plus (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Riopan (containing Magaldrate, Simethicone)Rolaids Multi-Symptom (containing Calcium Carbonate, Magnesium Hydroxide, Simethicone)Rolaids Plus Gas Relief (containing Calcium Carbonate, Simethicone)Rulox Plus (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)Titralac Plus (containing Calcium Carbonate, Simethicone)Valumag Plus (containing Aluminum Hydroxide, Magnesium Hydroxide, Simethicone)

Quick Jump:Kitchen Foods (0)Drug Red Flags (0)Supplements & Herbs (0)Administration Timing (1)

Kitchen Food, Drink & Dietary Conflicts

Biochemical interactions with common foods, beverages & cooking ingredients

0 Flagged Foods

Unless your physician explicitly directs otherwise, continue your normal balanced diet while taking this medication. Maintain consistent hydration and meal intervals.

Prescription & OTC Drug Interactions (DDI)

Documented pharmacological conflicts & contraindicated co-prescriptions

0 Warning Classes

No major contraindicated drug classes listed in the basic monograph. Always provide your complete medication list to your prescribing physician.

Dietary Supplements, Herbs & Minerals (DNI)

Interactions with over-the-counter vitamins, minerals, and herbal preparations

0 Monitored

No acute supplement or herb contraindications identified. Notify your healthcare provider of any multi-vitamins or botanicals you take daily.

Chronotherapy & Meal Administration Protocols

Optimal absorption, meal-timing rules & GI tolerability protocols

1 Protocols

MEALMealtime Administration

It usually is taken four times a day, after meals and at bedtime.

Rationale: Food enhances bioavailability, prevents gastric mucosal irritation, or stabilizes peak-to-trough pharmacokinetic variations.

Multi-Substance Interactive Radar

Taking Simethicone alongside daily coffee, supplements, or other medications?

Add all your daily medications, foods (Dairy, Spinach, Coffee, Grapefruit), and botanicals (Ashwagandha, Curcumin, Melatonin) into the SafeStack interactive engine to run full multi-way synergy collision analysis in real time.

Launch SafeStack Radar with Simethicone→

Authoritative Clinical Evidence & Regulatory Sources

Data on this clinical monograph is compiled from the U.S. National Library of Medicine (MedlinePlus), openFDA Structured Product Labeling (SPL Section 7 Drug Interactions), the NIH Office of Dietary Supplements (ODS), and Krause and Mahan's Food & Nutrition Care Process.

View Original NLM MedlinePlus Monograph·Clinical & Legal Disclaimers