Prescription Clinical MonographPrescription Therapeutic Agent
Verified Evidence Sources: openFDA & NLM MedlinePlus

Erythromycin and Sulfisoxazole

Comprehensive clinical interaction and dietary monograph for Erythromycin and Sulfisoxazole (Erythromycin and Sulfisoxazole).

Generic Active Chemical: Erythromycin and Sulfisoxazole
Brand Formulations:Eryzole¶Ilosone¶Pediazole¶

Kitchen Food, Drink & Dietary Conflicts

Biochemical interactions with common foods, beverages & cooking ingredients
1 Flagged Foods
Official Patient Dietary Instruction (NLM MedlinePlus)

Do not take this medication with, or just after, fruit juices, carbonated drinks, or tea. It can be taken with or between meals.

HIGH

Green Tea, Black Tea & Matcha (Tannins & OATP Inhibitors)

NutriDive Kitchen Food Biochemical Ontology & openFDA
Bioactive Compound:Polyphenolic Tannins & Catechins (EGCG)
Biological Target:Ionic Iron Transporters & OATP1A2 / OATP2B1
Clinical Mechanism:

Tannins form insoluble macromolecular iron-tannate precipitates, dropping non-heme iron absorption by up to 80%. Catechins additionally inhibit intestinal OATP uptake transporters, drastically reducing bioavailability of beta-blockers (atenolol) and allergy medications (fexofenadine).

Patient Actionable Rule:Do not take oral iron supplements with tea; drink tea between meals at least 2 hours apart. If taking fexofenadine or nadolol, avoid green tea within 4 hours.

Prescription & OTC Drug Interactions (DDI)

Documented pharmacological conflicts & contraindicated co-prescriptions
0 Warning Classes
No major contraindicated drug classes listed in the basic monograph. Always provide your complete medication list to your prescribing physician.

Dietary Supplements, Herbs & Minerals (DNI)

Interactions with over-the-counter vitamins, minerals, and herbal preparations
0 Monitored
No acute supplement or herb contraindications identified. Notify your healthcare provider of any multi-vitamins or botanicals you take daily.

Chronotherapy & Meal Administration Protocols

Optimal absorption, meal-timing rules & GI tolerability protocols
1 Protocols
MEALAdministration Rule

Drink a full glass of water after each dose.

Rationale: Promotes optimal mucosal absorption and consistent therapeutic plasma levels.

Multi-Substance Interactive Radar

Taking Erythromycin and Sulfisoxazole alongside daily coffee, supplements, or other medications?

Add all your daily medications, foods (Dairy, Spinach, Coffee, Grapefruit), and botanicals (Ashwagandha, Curcumin, Melatonin) into the SafeStack interactive engine to run full multi-way synergy collision analysis in real time.

Launch SafeStack Radar with Erythromycin and Sulfisoxazole→
Authoritative Clinical Evidence & Regulatory Sources

Data on this clinical monograph is compiled from the U.S. National Library of Medicine (MedlinePlus), openFDA Structured Product Labeling (SPL Section 7 Drug Interactions), the NIH Office of Dietary Supplements (ODS), and Krause and Mahan's Food & Nutrition Care Process.